|
| U.S. Brand
Names |
|
| E-Pilo-x® Ophthalmic;
PxEx®
Ophthalmic |

|
|
| Generic
Available |
|
|
No |

|
|
| Canadian Brand
Names |
|
| E-Pilo® |

|
|
| Synonyms |
|
|
Epinephrine and Pilocarpine |

|
|
| Pharmacological Index |
|
|
Ophthalmic Agent, Antiglaucoma; Ophthalmic Agent, Miotic |

|
|
| Use |
|
|
Treatment of glaucoma; counter effect of cycloplegics |

|
|
| Pregnancy Risk
Factor |
|
|
C |

|
|
| Contraindications |
|
|
Hypersensitivity to pilocarpine, epinephrine, or any component; acute
inflammatory disease of anterior chamber |

|
|
| Adverse
Reactions |
|
|
1% to 10%:
Central nervous system: Headache
Dermatologic: Stinging, itching
Gastrointestinal: Salivation
Hematologic: Vitreous hemorrhages
Ocular: Miosis, ciliary spasm, blurred vision, retinal detachment,
lacrimation, photophobia, acute iritis
Miscellaneous: Hypersensitivity reactions |

|
|
| Stability |
|
|
Store at 8°C to 30°C
(46°F to 86°F); keep tightly closed;
do not use solution if it is brown or contains a precipitate; protect from heat
and light |

|
|
| Usual Dosage |
|
|
Instill 1-2 drops up to 6 times/day |

|
|
| Mental Health: Effects
on Mental Status |
|
|
None reported |

|
|
| Mental Health:
Effects on Psychiatric
Treatment |
|
|
Pilocarpine may antagonize the effects of anticholinergic and produce cardiac
conduction abnormalities in patients receiving
beta-blockers |

|
|
| Dental Health: Local
Anesthetic/Vasoconstrictor
Precautions |
|
|
No information available to require special precautions |

|
|
| Dental Health:
Effects on Dental Treatment |
|
|
No effects or complications reported |

|
|
| Patient
Information |
|
|
See individual agents. Pregnancy/breast-feeding precautions: Inform
prescriber if you are or intend to get pregnant. Consult prescriber if
breast-feeding. |

|
|
| Nursing
Implications |
|
|
Usually causes difficulty in dark adaptation; advise patients to use caution
while night driving or performing hazardous tasks in poor
illumination |

|
|
| Dosage Forms |
|
|
Solution, ophthalmic: Epinephrine bitartrate 1% and pilocarpine hydrochloride
1%, 2%, 3%, 4%, 6% (15 mL) |

|
|
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